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Follow the directions on the prescription label. Swallow the tablets with a drink of water. If you take the tablets once a day, it is best to take your dose in the evening hours (like with the evening meal) or at bedtime. You may take this medicine with or without food. Do not take simvastatin with grapefruit juice; orange juice may be used instead. Take your doses at regular intervals. Do not take your medicine more often than directed.<br /> <br /> Contact your pediatrician or health care professional regarding the use of this medicine in children. Special care may be needed.<br /> <h3><u>What if I miss a dose?</u></h3><br /> If you miss a dose, take it as soon as you can. If it is almost time for your next dose, take only that dose. 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Also tell your prescriber or health care professional if you are a frequent user of drinks with caffeine or alcohol, if you smoke, or if you use illegal drugs. These may affect the way your medicine works. 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Your physician or dietician can suggest a low-cholesterol and low-fat diet that will reduce your risk of getting heart and blood vessel disease. Avoid alcohol and smoking, and keep a proper exercise schedule.<br /> <br /> If you are going to have surgery tell your prescriber or health care professional that you are taking simvastatin.<br /> <br /> This medicine should not be used by women who are pregnant or breast-feeding. There is a potential for serious side effects to an unborn child or to an infant. Talk to your health care professional or pharmacist for more information.</p> <div><br /> <h3><u>Where can I keep my medicine?</u></h3><br /> Keep out of the reach of children in a container that small children cannot open.<br /> <br /> ,<h2>What is/are Zocor?</h2> <p>SIMVASTATIN is known as a HMG-CoA reductase inhibitor or 'statin'. It lowers the level of cholesterol and triglycerides in the blood. 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Do not take double or extra doses.</p> <h2>What may interact with this medicine?</h2> <p>Do not take this medicine with any of the following:</p> medicines for fungal infections like itraconazole, ketoconazole nefazodone other medicines for high cholesterol red yeast rice some antibiotics like clarithromycin, erythromycin, telithromycin some medicines for HIV infection like amprenavir, indinavir, ritonavir <p>This medicine may also interact with the following:</p> alcohol amiodarone cyclosporine danazol diltiazem grapefruit juice fluconazole verapamil voriconazole warfarin <p>This list may not describe all possible interactions. Give your health care providers a list of all the medicines, herbs, non-prescription drugs, or dietary supplements you use. Also tell them if you smoke, drink alcohol, or use illegal drugs. 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